Combination Therapy for Sleeping Sickness: A Wake‐Up Call
نویسندگان
چکیده
منابع مشابه
Combination therapy for sleeping sickness: a wake-up call.
Ours is a smaller world than that of previous generations. Given humankind's insatiable desire to change places for all kinds of reasons and through all kinds of routes, clinicians in developed countries are increasingly exposed to diseases that used to be considered " exotic. " Cases of African trypanosomiasis, the archetype of such diseases ever since Joseph Conrad's Heart of Darkness, are no...
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Fatal if untreated, human African trypanosomiasis (HAT; sleeping sickness) afflicts an estimated 50,000–70,000 people each year [1], all in sub-Saharan Africa, with only a minority of cases (nearly 12,000 in 2008) being reported [2]. HAT is one of four neglected tropical diseases (NTDs) identified by the World Health Organization (WHO) as requiring Innovative and Intensified Disease Management ...
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BACKGROUND Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are either highly toxic or impracticable in field conditions. We compared the efficacy and safety of the nifurtimox-eflornithine drug combination with the standard eflornithine regimen for the treatment of second-stage disease. ME...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2007
ISSN: 0022-1899,1537-6613
DOI: 10.1086/510540